Source: CTD_human

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms 		0.600 Biomarker CTD_human Caveolin-1 promotes the tumor suppressor properties of oncogene-induced cellular senescence. 29247004

2018
Entrez Id: 2067
Gene Symbol: ERCC1
ERCC1
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms 		0.580 Biomarker CTD_human Rs3212986 polymorphism, a possible biomarker to predict smoking-related lung cancer, alters DNA repair capacity via regulating ERCC1 expression. 30453383

2018
Entrez Id: 857
Gene Symbol: CAV1
CAV1
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms 		0.320 Biomarker CTD_human A lack of K-Ras<sup>G12D</sup>-induced premature senescence in caveolin-1-null mice results in the formation of more abundant lung tumors. 29247004

2018
Entrez Id: 3950
Gene Symbol: LECT2
LECT2
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms 		0.300 Therapeutic CTD_human Leukocyte Cell-Derived Chemotaxin 2 Retards Non-Small Cell Lung Cancer Progression Through Antagonizing MET and EGFR Activities. 30453282

2018
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms 		0.700 Biomarker CTD_human The ISG15-specific protease USP18 regulates stability of PTEN. 27980214

2017
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms 		0.600 Biomarker CTD_human Evolution and clinical impact of co-occurring genetic alterations in advanced-stage EGFR-mutant lung cancers. 29106415

2017
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms 		0.600 Biomarker CTD_human Bronchial airway gene expression signatures in mouse lung squamous cell carcinoma and their modulation by cancer chemopreventive agents. 27935865

2017
Entrez Id: 7161
Gene Symbol: TP73
TP73
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms 		0.340 Biomarker CTD_human TAp73 upregulates IL-1β in cancer cells: Potential biomarker in lung and breast cancer? 28212736

2017
Entrez Id: 4170
Gene Symbol: MCL1
MCL1
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms 		0.330 Biomarker CTD_human Bronchial airway gene expression signatures in mouse lung squamous cell carcinoma and their modulation by cancer chemopreventive agents. 27935865

2017
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms 		0.330 Biomarker CTD_human TAp73 upregulates IL-1β in cancer cells: Potential biomarker in lung and breast cancer? 28212736

2017
Entrez Id: 2237
Gene Symbol: FEN1
FEN1
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms 		0.320 Biomarker CTD_human FEN1 promotes tumor progression and confers cisplatin resistance in non-small-cell lung cancer. 28371273

2017
Entrez Id: 3084
Gene Symbol: NRG1
NRG1
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms 		0.310 Biomarker CTD_human Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes. 28604730

2017
Entrez Id: 5654
Gene Symbol: HTRA1
HTRA1
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms 		0.310 Biomarker CTD_human Bronchial airway gene expression signatures in mouse lung squamous cell carcinoma and their modulation by cancer chemopreventive agents. 27935865

2017
Entrez Id: 79365
Gene Symbol: BHLHE41
BHLHE41
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms 		0.310 Biomarker CTD_human Bronchial airway gene expression signatures in mouse lung squamous cell carcinoma and their modulation by cancer chemopreventive agents. 27935865

2017
Entrez Id: 2729
Gene Symbol: GCLC
GCLC
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms 		0.310 Biomarker CTD_human Bronchial airway gene expression signatures in mouse lung squamous cell carcinoma and their modulation by cancer chemopreventive agents. 27935865

2017
Entrez Id: 810
Gene Symbol: CALML3
CALML3
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms 		0.310 Biomarker CTD_human Bronchial airway gene expression signatures in mouse lung squamous cell carcinoma and their modulation by cancer chemopreventive agents. 27935865

2017
Entrez Id: 4082
Gene Symbol: MARCKS
MARCKS
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms 		0.310 Biomarker CTD_human Bronchial airway gene expression signatures in mouse lung squamous cell carcinoma and their modulation by cancer chemopreventive agents. 27935865

2017
Entrez Id: 3491
Gene Symbol: CCN1
CCN1
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms 		0.310 Biomarker CTD_human Bronchial airway gene expression signatures in mouse lung squamous cell carcinoma and their modulation by cancer chemopreventive agents. 27935865

2017
Entrez Id: 1958
Gene Symbol: EGR1
EGR1
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms 		0.310 Biomarker CTD_human Bronchial airway gene expression signatures in mouse lung squamous cell carcinoma and their modulation by cancer chemopreventive agents. 27935865

2017
Entrez Id: 1363
Gene Symbol: CPE
CPE
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms 		0.300 Biomarker CTD_human Bronchial airway gene expression signatures in mouse lung squamous cell carcinoma and their modulation by cancer chemopreventive agents. 27935865

2017
Entrez Id: 5473
Gene Symbol: PPBP
PPBP
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms 		0.300 Biomarker CTD_human Bronchial airway gene expression signatures in mouse lung squamous cell carcinoma and their modulation by cancer chemopreventive agents. 27935865

2017
Entrez Id: 11274
Gene Symbol: USP18
USP18
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms 		0.300 Biomarker CTD_human The ISG15-specific protease USP18 regulates stability of PTEN. 27980214

2017
Entrez Id: 6662
Gene Symbol: SOX9
SOX9
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms 		0.300 Biomarker CTD_human Bronchial airway gene expression signatures in mouse lung squamous cell carcinoma and their modulation by cancer chemopreventive agents. 27935865

2017
Entrez Id: 60370
Gene Symbol: AVPI1
AVPI1
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms 		0.300 Biomarker CTD_human Bronchial airway gene expression signatures in mouse lung squamous cell carcinoma and their modulation by cancer chemopreventive agents. 27935865

2017
Entrez Id: 1212
Gene Symbol: CLTB
CLTB
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms 		0.300 Biomarker CTD_human Bronchial airway gene expression signatures in mouse lung squamous cell carcinoma and their modulation by cancer chemopreventive agents. 27935865

2017